RNA-phosphoproteome correlation - all-phosphoproteome

This report summarizes the correlation analysis between RNA and phosphoproteome expression. Correlations are calculated per gene (across samples) and per sample (across genes) using Pearson’s correlation coefficient.


Gene-wise correlations

The histogram shows all gene-wise correlations (blue) across 77 samples. Significant correlations (FDR adjusted p-values < 0.05) are depicted in red. You can enable/disable layers of the histogram by clicking on the respective legend. The dashed line depicts the median correlation based on all genes.


Summary table

No. of correlations all negative positive median cor.
all 6343 444 5899 0.3362514
FDR 5% 3788 11 3777 0.4534647

Correlation-rank-plot

Genes are ranked according to their RNA / phosphoproteome correlation (x-axis) and plotted against the actual correlation value (y-axis). Gene names can be inferred by hovering over the data points.

Top 10 correlated genes

Left: positive correlation; right: negative correlation
geneSymbol correlation p.value p.value.fdr
TMEM139 0.8972172 0e+00 0e+00
TRIM36 0.8599384 0e+00 0e+00
TSNARE1 0.8532321 0e+00 0e+00
KCNE4 0.8416940 0e+00 0e+00
NSMF 0.8387011 0e+00 3e-07
NFIB 0.8383407 0e+00 0e+00
HEBP1 0.8369791 1e-07 5e-07
KANK1 0.8351589 0e+00 0e+00
RBBP8 0.8328975 0e+00 0e+00
DIAPH3 0.8325831 0e+00 0e+00
geneSymbol correlation p.value p.value.fdr
VSIG1 -0.4949413 0.0139356 0.0255621
PLK3 -0.4225146 0.0224102 0.0389873
PIGK -0.4225092 0.0353724 0.0578271
KIF5A -0.3863381 0.0289546 0.0486385
RPS9 -0.3737538 0.0866268 0.1257665
COL11A1 -0.3660082 0.1027313 0.1457448
CHAF1B -0.3454521 0.0025741 0.0057858
EIF4G2 -0.3438002 0.0022031 0.0050522
CAMTA2 -0.3434564 0.0110003 0.0206496
ERI3 -0.3349811 0.0814238 0.1194153

Sample-wise correlations

For each of the 77 samples Pearson correlations between RNA / phosphoproteome across all genes were calculated and are depicted as bubble chart. The size of each bubble scales with correlation value.



Created on 2020-11-12 20:28:06