RNA-phosphoproteome correlation - all-phosphoproteome

This report summarizes the correlation analysis between RNA and phosphoproteome expression. Correlations are calculated per gene (across samples) and per sample (across genes) using Pearson’s correlation coefficient.

Gene-wise correlations

The histogram shows all gene-wise correlations (blue) across 77 samples. Significant correlations (FDR adjusted p-values < 0.05) are depicted in red. You can enable/disable layers of the histogram by clicking on the respective legend. The dashed line depicts the median correlation based on all genes.

Summary table

No. of correlations	all	negative	positive	median cor.
all	6343	444	5899	0.3362514
FDR 5%	3788	11	3777	0.4534647

Correlation-rank-plot

Genes are ranked according to their RNA / phosphoproteome correlation (x-axis) and plotted against the actual correlation value (y-axis). Gene names can be inferred by hovering over the data points.

Top `10` correlated genes

Left: positive correlation; right: negative correlation

geneSymbol	correlation	p.value	p.value.fdr
TMEM139	0.8972172	0e+00	0e+00
TRIM36	0.8599384	0e+00	0e+00
TSNARE1	0.8532321	0e+00	0e+00
KCNE4	0.8416940	0e+00	0e+00
NSMF	0.8387011	0e+00	3e-07
NFIB	0.8383407	0e+00	0e+00
HEBP1	0.8369791	1e-07	5e-07
KANK1	0.8351589	0e+00	0e+00
RBBP8	0.8328975	0e+00	0e+00
DIAPH3	0.8325831	0e+00	0e+00

geneSymbol	correlation	p.value	p.value.fdr
VSIG1	-0.4949413	0.0139356	0.0255621
PLK3	-0.4225146	0.0224102	0.0389873
PIGK	-0.4225092	0.0353724	0.0578271
KIF5A	-0.3863381	0.0289546	0.0486385
RPS9	-0.3737538	0.0866268	0.1257665
COL11A1	-0.3660082	0.1027313	0.1457448
CHAF1B	-0.3454521	0.0025741	0.0057858
EIF4G2	-0.3438002	0.0022031	0.0050522
CAMTA2	-0.3434564	0.0110003	0.0206496
ERI3	-0.3349811	0.0814238	0.1194153

Sample-wise correlations

For each of the 77 samples Pearson correlations between RNA / phosphoproteome across all genes were calculated and are depicted as bubble chart. The size of each bubble scales with correlation value.